Automated Solutions For Ion Channel Analysis
with Sophion Bioscience
Automated Patch Clamp of lysosomal ion channels was achieved using LYSO-Prep™, enabling measurement of TRPML1 activity.
Focus Areas
Exploring the subcellular world of organelles.
Uncover their role across therapeutic areas and research applications, from discovery to clinical translation.
Therapeutic Areas
Organelles are central to the molecular mechanisms driving some of the most prevalent and complex human diseases. From impaired lysosomal clearance in neurodegeneration to mitochondrial stress in cancer and
metabolic disorders, subcellular dysfunction is a shared hallmark across therapeutic areas. Understanding these mechanisms at the organelle level opens new avenues for target identification and drug intervention.
Application Areas
Whether you are an academic researcher, part of a CRO, or developing a new drug, our purified organelle preparations support a broad range of research applications. From electrophysiology and enzyme activity
assays to high-throughput screening and biomarker discovery, our preparations are designed to deliver native-state biology wherever you need subcellular resolution.
KEY PARTNERS •
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LYSO-Prep™ A New Tool For Organellar Electrophysiology
with Nanion Technologies
LYSO-Prep™ overexpressing TRPML1 channels, was successfully characterized using APC and SSME high throughput platforms.
New frontier: Investigating lysosomal ion channels at body temperatures
with Nanion Technologies
Regulation of LYSO-Prep™ TMEM175 channels, at elevated temperatures in the native system using APC.